Overview

Treatment of Neuroendocrine Tumors (NETs) With Combination of Everolimus and Radiolabeled Somatostatin Analogue

Status:
Unknown status
Trial end date:
2018-12-01
Target enrollment:
Participant gender:
Summary
NET originate in neuroendocrine cells throughout the body. The goal of this study is to assess the safety and efficacy of the combination of everolimus and the intravenous radiolabeled Lu-177 DOTATATE Therapy as a 1st line therapy in unresectable well to moderately differentiated metastatic neuroendocrine tumors of all GI, lung and pancreatic origins. This is a phase 1 - 2 study. The phase 1 part involves finding the maximum tolerating dose (MTD) of Everolimus.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
King Faisal Specialist Hospital & Research Center
Treatments:
Everolimus
Sirolimus
Somatostatin