Overview

Treatment of Keratoconus Using Collagen Cross-Linking

Status:
Unknown status
Trial end date:
2011-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine the effectiveness of collagen cross-linking in the cornea in halting the progression and possibly partially reversing the effects of keratoconus. Keratoconus is a progressive weakening in the cornea that causes irregular astigmatism and thinning of the cornea. The overall effect is reduction of vision, and in more advanced cases, scarring of the cornea that may lead to the need for corneal transplantation. Cross-linking has been shown increase the rigidity of the cornea. The patients would be treated once and then followed over 24 months. .
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
University at Buffalo
Treatments:
Flavin Mononucleotide
Lidocaine
Pharmaceutical Solutions
Riboflavin