Treatment of Infertility in Women With Polycystic Ovary Syndrome

• Status: Completed
• Trial end date: 2006-02-01
• Target enrollment: 0
• Participant gender: Female

Summary

Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder affecting up to 10% of women. The primary symptoms of PCOS are menstrual irregularities, increased body and facial hair, acne, and infertility. This study will test a combination of medications in women with PCOS to determine which works best to overcome infertility.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
• Treatments: Citric Acid; Clomiphene; Enclomiphene; Metformin; Zuclomiphene

Criteria

Inclusion Criteria

• Eight or fewer menstrual cycles in the past year or intermenstrual periods of 45 days or longer

• Elevated testosterone level

• Good general health

• Sperm concentration in partner of 20 million/ml or greater

• Ability to have intercourse 2-3 times per week

• One functional fallopian tube and normal uterine cavity