Treatment of Hyperuricemia With Rasburicase in Patients With Acute Lymphoblastic Leukemia or High Grade Lymphoma
Status:
Completed
Trial end date:
2008-05-01
Target enrollment:
Participant gender:
Summary
In this study the efficacy and tolerability of two approaches to treat and prevent
hyperuricemia is tested in patients with acute lymphoblastic leukemia or high-grade lymphoma
with high risk of tumor lysis syndrome. Both arms are compared by randomisation. In one arm
patients receive during pre-phase chemotherapy conventional prophylaxis with allopurinol
whereas in the other arm Rasburicase is used.