Treatment of Giardia Lamblia Infections in Children

• Status: Terminated
• Trial end date: 2019-12-31
• Target enrollment: 0
• Participant gender: All

Summary

This study investigates the efficacy and safety of rectally administered metronidazole for pediatric Giardia lamblia infection, as well as the acceptance of this treatment regimen by patients/caregivers. The investigators hypothesize that rectal metronidazole is non-inferior to single-dose of oral tinidazole and will cure at least 72% of patients, a well as will be tolerated as good as tinidazole.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Helsinki University Central Hospital
• Treatments: Metronidazole; Tinidazole

Criteria

Inclusion Criteria:

• clinical symptoms could be explained by giardiasis AND

• fecal samples will test positive for the presence of G.lamblia in Uusimaa laboratory (HUSLAB)

Exclusion Criteria:

• age <6 mo or >10 years

• weight <9.5 kg

• the absence of symptoms

• co-infection with another pathogen, which may cause giardiasis-like symptoms