Treatment of Fatigue With Methylphenidate, Modafinil and Amantadine in Multiple Sclerosis
Status:
Completed
Trial end date:
2019-11-21
Target enrollment:
Participant gender:
Summary
Randomized, placebo-controlled, crossover, 4-sequence, 4-period, double-blind (participants
and investigators), multicenter trial of 3 commonly used medications for treatment of
MS-related fatigue (amantadine, modafinil, methylphenidate) versus placebo in fatigued
subjects with MS defined by McDonald Criteria.