Treatment of Facial Burns With Flammacerium Compared to Flammazine and the Impact of Facial Burns on Psychosocial Wellbeing
Status:
Completed
Trial end date:
2008-12-01
Target enrollment:
Participant gender:
Summary
The face is involved in 40-50% of patients with burns admitted to the Dutch Burn Centres.
Scarring of the face as a consequence of burns will often have a detrimental effect on
function and aesthetics, and may cause negative effects on psychosocial wellbeing. What the
best treatment is for facial burns, minimising scarring, is unclear. Besides that, there is
little empirical evidence regarding the impact of facial scarring on psychosocial wellbeing.
In clinical practice good results are felt to be achieved by treatment of facial burns with
flammacerium. To substantiate the perceived advantages of flammacerium, its efficacy is
compared to flammazine, a current alternative of care. The efficacy of treatment will be
assessed in a prospective randomised multicentre clinical trial. Efficacy will be analysed in
terms of number of patients requiring surgery and functional and aesthetic outcome.
Apart from medical outcome, this study offers the opportunity to study psychosocial problems
associated with facial defects. It is still an unresolved question whether facial scarring
causes more or different psychosocial problems. Therefore, self-esteem and quality of life
will be examined over time, in relation to depression, posttraumatic stress symptoms and
other factors, such as coping style and social support.
By evaluating the efficacy of different treatment strategies, we aim to optimise the standard
of care of facial burns. Furthermore, this study wants to shed more light on the psychosocial
impact of facial injury. With these results psychosocial professionals will be able to focus
on persons at risk and to be better able to meet a patient's personal needs.