Treatment of Dysphagia and Ineffective Esophageal Motility With Prucalopride: A Pilot Study
Status:
Completed
Trial end date:
2019-12-02
Target enrollment:
Participant gender:
Summary
This study will test prucalopride (a prokinetic drug currently approved by Health Canada for
treatment of constipation) as a treatment for Ineffective Esophageal Motility (IEM). Adult
patients with previously diagnosed IEM will be invited to participate by the investigators.
The participants will take the study medication for 5 days and on the final day of medication
undergo an esophageal manometry procedure at the Calgary Gut Motility Centre to measure
esophageal function. Symptoms and side effects will be tracked at baseline and on Day 5.