Treatment of Coronary Atherosclerosis by Insulin Sensitizers in Insulin-Resistant Patients
Status:
Unknown status
Trial end date:
2007-12-01
Target enrollment:
Participant gender:
Summary
In this study, we, the investigators at National Taiwan University Hospital, will evaluate
the efficacy of pharmacological therapy targeted to reduce insulin resistance (pioglitazone)
on the progression and compositional change of non-obstructive coronary atherosclerotic
plaques and coronary calcification by serial intravascular ultrasound
(IVUS)/multi-detector-row computed tomography (MDCT) follow-up in patients with type 2
diabetes or non-diabetic metabolic syndrome during a 2-year period.