Treatment of Chronic Obstructive Pulmonary Disease (COPD) With Iodinated Activated Charcoal
Status:
Completed
Trial end date:
2013-05-01
Target enrollment:
Participant gender:
Summary
The purpose of this study s to determine whether treatment with Iodinated Active Charcoal can
improve lung function and physical capacity in patients with chronic obstructive lung
disorders. The rational for the study is the observation that COPD patients have an increased
tissue load of mercury interfering with the function by NeuroEpithelial Endocrine (NEE) cells
in the respiratory tract. Mercury binding to these NEE cells leads to an increased smooth
muscle tonus and a reduced response to bronchodilator treatment. Initial observational data
have shown an improved lung function and improved functional capacity after treatment
motivating a larger placebo controlled POC study