Overview

Treatment of Chronic Hand Eczema With Oral Roflumilast (HERO)

Status:
Not yet recruiting
Trial end date:
2026-04-01
Target enrollment:
Participant gender:
Summary
This study is a multicentre, double-blinded, randomized, placebo-controlled, clinical trial with open-label extension. The purpose and aim of this study is to investigate the efficacy and safety of roflumilast (PDE4-inhibitor) in adult patients with chronic hand eczema (CHE). Patients will receive 16-week treatment with either roflumilast or placebo tablets. Hereafter, both groups continue in open-label treatment for 12 weeks where both groups will receive treatment with roflumilast.
Phase:
Phase 4
Details
Lead Sponsor:
Jacob Pontoppidan Thyssen
Collaborator:
The Novo Nordic Foundation