Treatment of Chronic Constipation in Parkinson's Disease

• Status: Completed
• Trial end date: 2016-12-20
• Target enrollment: 0
• Participant gender: All

Summary

Chronic constipation is the most common gastrointestinal symptom reported by PD patients; it could be one of the manifestations of disease onset.

PHGG fiber is extracted from a herbaceous plant (Cyamopsis Tetra-Gonolobus, family:

Leguminosae) of Indian origin: it produces 5/9 pods containing seeds which produce the famous guar gum, that is a natural polysaccharide.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: IRCCS San Raffaele

Criteria

Inclusion Criteria:

• Idiopathic PD according to UK PDS Brain Bank Clinical Diagnostic Criteria.

• Chronic constipation according to Roma III criteria for chronic functional constipation lasting from at least 6 months.

• Absence of dementia.

• Patients who are able to understand and sign the informed consent for participation in the study

Exclusion Criteria:

• People who suffer from other comorbidities that could interfere with the results of the study according to the investigator.

• People who are not able to provide reliable answers to the questionnaire according to the opinion of the investigator.

• Inclusion in other clinical trials at the time of the visit.