Overview

Treatment of Candidal Vulvovaginitis Using Cumin Seed Extract Vaginal Suppositories.

Status:
Completed
Trial end date:
2020-01-31
Target enrollment:
0
Participant gender:
Female
Summary
Fungal infections have increased over the last two decades, largely because of the increasing size of the population at risk, including patients who are immunocompromised, broad-spectrum antibiotics and intravascular catheter users. Essential oils and other extracts of plants have evoked interest as sources of natural products. They have been shown to possess antibacterial, antifungal, antiviral, insecticidal and antioxidant properties. To the best of our knowledge, no study has examined the efficacy of cumin seed extract on relieving vulvovaginal candidiasis in vivo.
Phase:
Phase 2/Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Assiut University
Treatments:
Clotrimazole
Miconazole
Criteria
Inclusion Criteria:

1. Women were 18-49 years old and were married;

2. They had not used antibiotics, immunosuppressive drugs, or vaginal drugs 14 days
before the study;

3. They did not suffer from trichomonal vaginitis, bacterial vaginitis, or cervicitis
based on direct smear;

4. Candidiasis culture was in agreement with clinical symptoms and patient's complaints.

Exclusion Criteria:

1. Pregnant and lactating women;

2. Those who had abnormal uterine bleeding;

3. Women with diabetes or autoimmune diseases;

4. Women refuse to participate in the study.