Treatment of Apomorphine-induced Skin Reactions: a Pilot Study
Status:
Unknown status
Trial end date:
2017-11-01
Target enrollment:
Participant gender:
Summary
Skin reactions as a result of continuous subcutaneous apomorphine infusion occur frequently
and interfere with the absorption of apomorphine. The histopathology of apomorphine-induced
skin reactions is poorly understood. Therefore treatment options are limited and suggestive.
Objective: to investigate the efficacy of four treatments including massage, dilution of
apomorphine, treatment with topical hydrocortisone and pre-treatment with subcutaneous
administered hydrocortisone, in Parkinson's disease patients with apomorphine-induced skin
reactions.