Overview

Treatment of Adults Aged Up to 60 Years With De Novo Acute Myeloblastic Leukaemia,Secondary AML, or RAEB-T

Status:
Unknown status
Trial end date:
2005-09-01
Target enrollment:
Participant gender:
Summary
This randomized phase II/III trial investigates the antileukemic activity and toxicity of the FLAG-Ida regimen as a second induction course in patients with acute myeloid leukaemia and bad response to the first induction cycle and/or with a high risk karyotype and compares the antileukemic activity and toxicity of high dose cytarabine/daunorubicin vs. autologous peripheral blood stem cell transplantation as late consolidation therapy in standard risk patients.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Hannover Medical School
Collaborators:
Ev. Krankenhaus Essen-Werden
Humboldt-Universität zu Berlin
Johann Wolfgang Goethe University Hospital
Klinikum Augsburg
Klinikum Hanover-Siloah Hospital
Klinikum Wuppertal GmbH
Medizinische Universitätsklinik Tübingen
Universitätsklinikum Hamburg-Eppendorf
University Hospital Augsburg
University Hospital Freiburg
University Hospital, Ghent
University of Ulm
Treatments:
Cytarabine
Daunorubicin
Etoposide
Fludarabine
Idarubicin