Overview

Treatment With IFN After Curative Resection of HCC in HCV-Related Cirrhosis

Status:
Completed
Trial end date:
2005-09-01
Target enrollment:
Participant gender:
Summary
We conducted a randomized controlled trial of adjuvant interferon (IFN) therapy in patients with hepatitis-C virus (HCV)-related cirrhosis who underwent curative resection of hepatocellular carcinoma (HCC) to investigate whether IFN could reduce or delay the incidence of recurrent tumor (secondary/tertiary prevention of HCC). Patients were randomly assigned to treatment with IFN (3MU thrice/wk /48 weeks) vs. no treatment after curative resection of HCC(control group)
Phase:
Phase 3
Details
Lead Sponsor:
National Cancer Institute, Milan
Collaborator:
Associazione Italiana per la Ricerca sul Cancro
Treatments:
Interferon alpha-2
Interferon-alpha
Interferons