Treatment With Acetyl-Choline Esterase Inhibitors in Children With Autism Spectrum Disorders
Status:
Unknown status
Trial end date:
2017-12-01
Target enrollment:
Participant gender:
Summary
We propose a study which will combine multiple modalities in evaluating the treatment
response of children with autism spectrum disorders (ASD) to acetyl-choline esterase (AChE)
inhibitors and choline supplements. The primary objective of the study is to examine the
efficacy of this treatment in improving core autistic symptoms. The Secondary objective of
the study is to evaluate the safety and tolerability of the treatment protocol in ASD
children. Exploratory objectives include evaluation of the influence of the treatment on
linguistic performance, comorbid behaviors, adaptive functioning and executive functions.
Phase:
Phase 4
Details
Lead Sponsor:
Sheba Medical Center
Collaborator:
The Israeli Society of Clinical Pediatrics (HIPAK)