Overview

Treatment Resistant Bipolar Depression

Status:
Terminated

Trial end date:
2010-01-01

Target enrollment:
0

Participant gender:
All

Summary

To determine if adding Escitalopram to current mood stabilizer (MS) or atypical antipsychotic (AA) will improve in rates similar to or better than adding a placebo (inactive pill)in resistant bipolar patients.

Phase:

Phase 1

Accepts Healthy Volunteers?

Accepts Healthy Volunteers

Details

Lead Sponsor:

Queen's University

Treatments:

Citalopram
Dexetimide

Criteria

Inclusion Criteria:

- Age 18 or older

- Diagnosis of Bipolar Disorder and currently be in depressive state, and not responded
to mood stabilizer or atypical antipsychotic alone or combined with an antidepressant
medication.

Exclusion Criteria:

- Pregnant or breastfeeding

- History of seizure disorder or other unstable medical condition

- Received Electroconvulsive Therapy or Transcranial Magnetic Stimulation in the last
three months

- Experienced hallucinations or delusions