Treating Brain Swelling in Pediatric Cerebral Malaria
Status:
Recruiting
Trial end date:
2023-11-30
Target enrollment:
Participant gender:
Summary
This study evaluates the effectiveness of two interventions in Malawian children with
cerebral malaria at high risk of death. One-third of the participants will receive treatment
as usual, one-third will receive treatment as usual and be placed on a mechanical ventilator,
and one-third will receive treatment as usual plus intravenous hypertonic saline.
Phase:
Phase 3
Details
Lead Sponsor:
Michigan State University
Collaborators:
Children's National Research Institute National Institute of Allergy and Infectious Diseases (NIAID) Nationwide Children's Hospital University of Malawi College of Medicine University of Maryland, Baltimore