Overview

Trazodone Dose Tolerance and APAP Adherence

Status:
Suspended
Trial end date:
2020-12-01
Target enrollment:
Participant gender:
Summary
Trazodone may help obstructive sleep apnea patients to stick to their therapy, but optimal dosing is unknown. This study looks at what dose of trazodone has the best balance of potential benefits to side-effects in people with obstructive sleep apnea who are either starting on positive airway pressure therapy or not adherent to it. Participants will be randomly assigned to one of three groups: trazodone 50 mg, trazodone 100 mg, or placebo for 14 days. The investigators will monitor side-effects and adherence to positive airway pressure therapy.
Phase:
Phase 1
Details
Lead Sponsor:
Louis Stokes VA Medical Center
Treatments:
Trazodone