Transversus Abdominis Plane Block for Laparoscopic Hysterectomy
Status:
Completed
Trial end date:
2013-03-01
Target enrollment:
Participant gender:
Summary
Purpose To evaluate whether adding a transversus abdominis plane block in patients undergoing
elective laparoscopic hysterectomy reduces Patient-controlled analgesia (PCA) morphine
requirements during the first 24 hours postoperatively.
Forty-six patients undergoing laparoscopic hysterectomy will be randomized into two groups:
1. Group treatment TAP (n=23) will receive the following analgesia:
- US guided transversus abdominis plane block performed with 40ml of 0.375%
levobupivacaine (20 ml per side) after general anaesthesia induction, before
surgical start
- Morphine PCA with loading dose i.v. titrated by the PACU nurse if pain > 5/10 at
rest
2. Group control will receive:
- Morphine PCA with loading dose i.v. titrated by the PACU nurse if pain > 5/10 at
rest
Primary Outcome Measures:
Morphine consumption (mg) (Time Frame: 24 hours) in Groups TAP and Control
Secondary Outcome Measures:
- Pain at rest and during movement quantified as Numerical Rating Scores (0-10) for pain
when resting in bed and during cough during the first 24 hours postoperatively
- Time to PACU dimission, evaluated as patient's achievement of a White's score > or =
12/14
- Time to home discharge, evaluated as patient's achievement of a PADDS score > or = 9
- Functional patient capacity as measured before surgery and whenever a White's score > or
= 12 will be reached (2minute walking test)
- Eventual side effects such as nausea/vomiting