Transversus Abdominis Plane Block Versus Wound Infiltration for Analgesia After Cesarean Delivery
Status:
Completed
Trial end date:
2021-08-01
Target enrollment:
Participant gender:
Summary
Adequate pain control after cesarean delivery is a major concern both for parturient and for
obstetric anesthesiologists, and it usually comprises a combination of systemic and regional
techniques.The transversus abdominis plane (TAP) block, affecting the nerves supplying the
anterior abdominal wall, is a recently introduced, promising regional analgesic technique for
a variety of abdominal and pelvic surgeries including cesarean delivery.(2,3) Infiltration of
local anesthetic into the surgical wound (either as a single shot or using indwelling
catheters) has long been used for postoperative analgesia.
Both the TAP block (4-6) and wound infiltration is superior to placebo; however, it is
unknown which of them provides better analgesia after cesarean delivery because of a scarcity
of randomized clinical trials. Only 2 studies compared the TAP block with wound infiltration
after cesarean delivery with conflicting results, and another study compared it with
continuous wound infusion and was prematurely terminated.
This study aimed to compare bilateral TAP block with single-shot local anesthetic wound
infiltration for analgesia after cesarean delivery performed under spinal anesthesia. We
hypothesized that the TAP block would decrease postoperative cumulative opioid consumption at
24 hours