Transporters for Organic Cations and Glycemic Control in Patients With Neuropathic Pain.
Status:
Completed
Trial end date:
2019-07-01
Target enrollment:
Participant gender:
Summary
This study aimed to investigate the influence of the glycemic control of type 2 diabetes
(DM2) and of cetirizine (OCTs inhibitor) on gabapentin kinetics disposition and
pharmacodynamics (PK-PD) in patients with neuropathic pain. Thus, non-diabetic patients
(Control Group, n=10), patients with controlled diabetes (n=9) and patients with uncontrolled
diabetes (n=10), all with neuropathic pain of intensity ≥ 4 in pain visual analog scale
(0-10) were investigated.