Transitioning Open Heart Surgery Patients From Insulin Infusions to Detemir

• Status: Completed
• Trial end date: 2010-06-01
• Target enrollment: 0
• Participant gender: All

Summary

In this study we will determine the proper method for transitioning patients from a continuous insulin infusion to periodic injections of a newer long-acting insulin called detemir (Levemir).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ohio State University
• Collaborator: Novo Nordisk A/S
• Treatments: Insulin; Insulin Detemir; Insulin, Globin Zinc

Criteria

Inclusion Criteria:

• diabetes mellitus

• post-cardiothoracic surgery

• requiring an insulin infusion of at least 1 unit/hour

• Age 18-75

Exclusion Criteria:

• Glucocorticoids

• total parenteral nutrition (TPN) or tube feeds

• Pregnancy

• Surgical procedures in the next 48 hours for whom intravenous (IV) insulin will be expected

• Expected length of stay less than 48 hours following cessation of the insulin drip

• Patients using subcutaneous insulin pumps

• Diabetic ketoacidosis

• End-stage renal disease

• End-stage liver disease

• Coma

• Potentially sensitive admissions: prisoners, human immunodeficiency virus(HIV), suicidality

• Unable to give consent in English