Overview

Transesophageal Magnetic Resonance Imaging (MRI) in Conjunction With Lipid Lowering Measures

Status:
Completed
Trial end date:
2004-04-01
Target enrollment:
Participant gender:
Summary
This research is being done to investigate the ability of an experimental imaging method - transesophageal magnetic resonance imaging (TEMRI), to detect the change in aortic atherosclerotic plaque burden and morphology between patients on high dose cholesterol lowering medications and patients on standard dose cholesterol lowering medications. This study will use TEMRI to see how atherosclerosis (cholesterol build up) changes with cholesterol lowering medications. This study will also investigate whether these cholesterol-lowering medications will change levels of blood tests, called inflammatory markers, in patients' blood. People with atherosclerosis may join this study. This study will also store blood samples for future studies of cardiac diseases; no gene testing will be done.
Phase:
N/A
Details
Lead Sponsor:
Johns Hopkins University
Collaborators:
Merck Sharp & Dohme Corp.
Surgi-Vision Inc
Treatments:
Simvastatin