Transdermal Nitroglycerin and Nifedipine in Preterm Labor
Status:
Completed
Trial end date:
2014-10-01
Target enrollment:
Participant gender:
Summary
One of the important complications of pregnancy is preterm labor (PTL) and delivery. There
are different tocolytic agents to enhance the time of delivery. The aim of this study was to
compare the effect of transdermal nitroglycerin (glyceryl trinitrate, GTN) and oral
nifedipine for managing preterm labor. This was a randomized clinical trial in women admitted
with diagnosis of PTL. Group one have received transdermal GTN whereas group two have
received oral nifedipine, vital signs, FHR, contractions, dilation and effacement as well as
gestation age at the time of delivery have been monitored and evaluated in both groups of
patient. Our main goal has been delay of delivery to have the most beneficial effect of
primary corticosteroid administration for fetus.