Transdermal Nicotine in Female Patients at High Risk for Post Operative Nausea and/or Vomiting (PONV)

• Status: Withdrawn
• Trial end date: 2012-04-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to see if the nicotine patch reduces post operative nausea and/or vomiting (PONV) among non-smoking patients who are at high risk of PONV.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Ochsner Health System
• Treatments: Nicotine

Criteria

Inclusion Criteria:

• age 18-65

• female

• health patient or acute illness

• undergoing outpatient-type general surgery, especially those associated with increased incidence of post-operative nausea and/or vomiting such as gynecological procedures

• undergoing general anesthesia for the surgery

• receiving opioids during surgery

• non-smokers

Exclusion Criteria:

• history of any heart condition

• history of uncontrolled hypertension, or presence of any condition that could be made drastically worse by an increase in blood pressure

• history of an aneurysm

• active tobacco use within the past five years

• works or lives in the presence of cigarette smoke

• pregnant

• mentally ill

• prisoners

• history of allergic reaction to nicotine or to adhesive patches

• history of allergic reaction to propofol, versed, fentanyl, zofran, decadron, and reglan