Tranexamic acid is an antifibrinolytic drug that has been used to decrease post-operative
blood loss. This study is a prospective, randomized controlled trial investigating the use of
tranexamic acid in fracture surgery around the hip and knee, in which significant blood loss
(>300mL) is expected.
The hypothesis of this study is that tranexamic acid will be associated with a decrease in
post-operative blood loss, as well as a decreased need for allogenic blood transfusion, in
patients who have fracture surgery around the hip and knee.