Tramadol/Acetaminophen(Ultracet) AS add-on Therapy in the Treatment of Patients With Ankylosing Spondylitis
Status:
Completed
Trial end date:
2009-07-01
Target enrollment:
Participant gender:
Summary
Tramadol 37.5 mg/APAP 325 mg combination tablets (ULTRACET®) were effective and safe as addon
therapy with COX-2 NSAID for treatment of osteoarthritis (5) and chronic low back pain
(6).There is no clinical trial regarding tramadol usage in chronic inflammatory arthritis
such as rheumatoid arthritis (RA) or ankylosing spondylitis. It would be important to do a
pilot clinical trial on add-on effect of tramadol to NSAID in patients with AS or RA.