Traditional Chinese Medicine Herbs in the Freeze-all IVF Cycle
Status:
Not yet recruiting
Trial end date:
2022-12-30
Target enrollment:
Participant gender:
Summary
In the early stage, the preliminary study found that traditional Chinese medicine (TCM)
intervention aimed at Nourishing kidney and regulating blood circulation in freeze-all IVF
cycles can improve the clinical pregnancy rate. In order to further study the role of TCM in
improving the pregnancy outcome of IVF-ET in infertility. A randomized controlled clinical
trial will be used in this study. 90 infertile patients are randomly divided into two groups.
The control group will be treated with conventional modern medicine, and the treatment group
will be treated with traditional Chinese herbs on the basis of conventional modern medicine.
The intervention starts from the 5th day of the menstrual cycle and lasts until the day
before IVF-ET. After the transplantation, the TCM treatment continues for 14 days. The number
of oocytes, antral follicles, AMH, serum FSH, and clinical pregnancy rate will be observed to
evaluate the effect of TCM herbs on the improvement of pregnancy outcomes. In addition, all
the participants will be asked to complete the self-evaluation of the anxiety/depression
scale on the 7th day of the menstrual cycle, before and after transplantation, to analyze the
emotional changes of the subjects during the study. The study will also observe the safety
and health economic indicators of TCM treatment, so as to improve the overall efficacy of TCM
Combined Application in assisted reproductive technology in the future.