Toxoplasmic Encephalitis in Patients With AIDS. Treatment and Prevention of Relapse

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

To compare pyrimethamine and intravenous (IV) clindamycin vs. pyrimethamine and sulfonamides in the treatment of AIDS patients with central nervous system (CNS) Toxoplasma gondii.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Palo Alto Medical Foundation
• Treatments: Clindamycin; Clindamycin palmitate; Clindamycin phosphate; Pyrimethamine

Criteria

Exclusion Criteria

Co-existing Condition:

Patients with the following conditions are excluded:

• Opportunistic infection (Pneumocystis carinii pneumonia (PCP), cryptococcal meningitis) or other conditions (brain abscess) which would make treatment results difficult to interpret due to concurrent infection, disease, or therapy.

Patients with other opportunistic infections or brain diseases are excluded.

Patients with AIDS and cerebral toxoplasmosis.