Overview

Total-Body Irradiation, Fludarabine, and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer

Status:
Completed
Trial end date:
2006-11-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Radiation therapy uses high-energy x-rays to damage cancer cells. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with donor peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combining total-body irradiation with fludarabine and donor peripheral stem cell transplantation in treating patients who have hematologic cancer.
Phase:
Phase 2
Details
Lead Sponsor:
Simmons Cancer Center
University of Texas Southwestern Medical Center
Treatments:
Cyclosporine
Cyclosporins
Fludarabine
Fludarabine phosphate
Mycophenolate mofetil
Mycophenolic Acid
Vidarabine