Topiramate Treatment of Alcohol Use Disorders in African Americans
Status:
Active, not recruiting
Trial end date:
2022-09-29
Target enrollment:
Participant gender:
Summary
The focus of this application is on the improvement of services for African American (AAs)
Veterans afflicted with an alcohol use disorder. The project focuses on the use of topiramate
as a treatment for alcohol use disorders. Despite having lower rates of heavy drinking than
European Americans (EAs), AAs have significantly higher rates of mortality from a variety of
alcohol-related conditions, including liver cirrhosis, accidents, and violence. Despite the
higher rates of morbidity and mortality, pharmacological treatments are understudied in this
population and there is some evidence that medications are less preferred and less effective
in AAs.