Topiramate Alone and in Combination With the Nicotine Patch for Smoking Cessation: A Pilot Study
Status:
Completed
Trial end date:
2013-08-01
Target enrollment:
Participant gender:
Summary
Specific aims:
1. To obtain pilot data on 4-week continuous quit rates associated with 10 weeks of
treatment with topiramate or placebo or topiramate plus nicotine patch for smoking
cessation.
2. To obtain pilot data on the effects of 10 weeks of topiramate versus placebo versus
combination of topiramate plus nicotine patch on nicotine withdrawal symptoms, smoking
satisfaction, and adverse effects during smoking cessation.
3. To obtain pilot data on weight gain over 10 weeks with topiramate versus placebo versus
combination of topiramate plus nicotine patch for smoking cessation.
Phase:
Phase 3
Details
Lead Sponsor:
UConn Health
Collaborators:
National Center for Research Resources (NCRR) National Institute on Alcohol Abuse and Alcoholism (NIAAA)