Topical Vitamin A Versus Vehicle Cream in the Treatment of Aged Skin

• Status: Completed
• Trial end date: 2002-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The objectives of this study are to evaluate the safety and efficacy of 0.5% retinol (Vitamin A) versus it's vehicle cream in the treatment and prevention of skin aging and Bateman's Purpura (bruising).

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Michigan
• Treatments: Retinol palmitate; Vitamin A

Criteria

Inclusion Criteria:

• Male and female

• 70 years of age or older

• history of Bateman's purpura on arms

• Relatively good general health and able to perform daily tasks

Exclusion Criteria:

• Sensitivity to any formulation ingredients

• History of Cardiovascular disease with continuing deficits (example: partial paralysis)

• Participated in any clinical trials within last 30 days

• Topical steroids or other drugs two weeks prior to study entry (short-term application of topical antimicrobials is allowed)

• Hormone replacement therapy within last 6 months.