Topical Versus Intravenous Tranexamic Acid in Total Knee Arthroplasty

• Status: Completed
• Trial end date: 2014-11-01
• Target enrollment: 0
• Participant gender: All

Summary

This clinical trial investigated two different routes of administration of tranexamic acid in total knee arthroplasty: topical compared to intravenous.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Irmandade da Santa Casa de Misericordia de Sao Paulo
• Treatments: Antifibrinolytic Agents; Pharmaceutical Solutions; Tranexamic Acid

Criteria

Inclusion Criteria: Patients in need of unilateral total knee arthroplasty (TKA) due to arthrosis, Albach grades III and IV were eligible

Exclusion Criteria:

• history or identified risk for deep vein thrombosis or pulmonary embolism

• history of coagulation or cardiovascular disorders

• vascular diseases

• pregnancy

• current use of anticoagulation drugs

• previous orthopedic surgery in the legs.