Topical Umbilical Cord Care for the Prevention of Colonization and Invasive Infections
Status:
Completed
Trial end date:
2013-07-01
Target enrollment:
Participant gender:
Summary
Umbilical catheters are necessary for many infants admitted to the Newborn Intensive Care
Unit (NICU)and utilized when indicated for up to 7 to 14 days. Bacterial colonization can
occur at the umbilical stump and potentially lead to serious bloodstream infections (BSIs).
This study is a prospective, randomized controlled feasibility trial to evaluate three types
of hygiene products on umbilical line stumps, on the effect of line colonization and
subsequent infections. Infants admitted to the NICU with an umbilical line(s) will be
randomized into one of four study groups, three products against standard of care (no
product). The three products that will be evaluated are currently being used in different
capacities for skin care in the UVA NICU. The study hypothesizes that daily topical
application of 1 or more antiseptic to the top of the umbilical stump will decrease
colonization of the umbilical stump while umbilical lines are in place.