Overview

Topical Tranexamic Acid Use on Granulating Wounds Following Mohs Micrographic Surgery

Status:
Recruiting
Trial end date:
2021-12-01
Target enrollment:
0
Participant gender:
All
Summary
Bleeding after Mohs micrographic surgery for skin cancer is a low risk complication that can occur. This study aims to determine the effect of a drug, often used to reduce bleeding, called tranexamic acid when applied topically to the skin wound after surgery.
Phase:
Early Phase 1
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
University of Missouri-Columbia
Treatments:
Tranexamic Acid
Criteria
Inclusion Criteria:

- All adult (18 years or older) patients presenting for Mohs micrographic surgery (MMS)
for the treatment of melanoma or nonmelanoma skin cancer (NMSC) with a wound that will
be healing by granulation

Exclusion Criteria:

- Patients must not be pregnant or breastfeeding.

- Patients must not have a known allergic reaction or sensitivity to TXA

- Patient must not have an international normalized ratio (INR) out of therapeutic range
if on warfarin.