Topical Tranexamic Acid (TXA) in Joint Arthroplasty
Status:
Completed
Trial end date:
2018-11-01
Target enrollment:
Participant gender:
Summary
The objective of this study is to evaluate the efficacy of topical tranexamic acid (TXA) in
decreasing blood loss following both shoulder arthroplasty and primary total hip
arthroplasty. TXA functions to decrease blood loss by affecting the blood clotting system
within the body. The investigators hypothesize that topical application of TXA prior to
closure reduces postoperative bleeding as measured by absolute changes in postoperative
hemoglobin levels and surgical drain output. In addition, use of topically applied tranexamic
acid may reduce the need for transfusions, the rates of hematomas, infections, and length of
hospital stay.