Topical Nitroglycerine Treatment for Radial Artery Spasm Prevention
Status:
Completed
Trial end date:
2019-05-02
Target enrollment:
Participant gender:
Summary
The primary objective of the study is to determine the role of transdermal vasodilators as an
adjunct to parenteral vasodilators in reducing radial artery spasm, improving patient
comfort, and post procedure radial artery patency during transradial coronary angiograms and
interventions. The study hypothesis is that transdermal vasodilators will increase radial
artery size and reduce radial artery spasm as well as improve patient comfort and post
procedure radial artery patency. This is a single-center, double-blind, randomized,
placebo-controlled study comparing the effect of transdermal preparations of lidocaine +
nitroglycerine and lidocaine + placebo on radial artery spasm in patients undergoing
transdermal coronary angiograms. Prior to the procedure, each patient will be randomized into
either the control arm, lidocaine + placebo, or study arm, lidocaine + nitroglycerine.
Phase:
Phase 4
Details
Lead Sponsor:
Aultman Health Foundation
Treatments:
Anesthetics Anesthetics, Local Lidocaine Nitroglycerin