Topical Imiquimod and Abraxane in Treating Patients With Advanced Breast Cancer
Status:
Completed
Trial end date:
2012-11-29
Target enrollment:
Participant gender:
Summary
This phase II trial is studying the side effects of giving topical imiquimod together with
Abraxane (paclitaxel albumin-stabilized nanoparticle formulation) to see how well it works in
treating patients with advanced breast cancer. Biological therapies, such as imiquimod, may
stimulate the immune system to kill tumor cells. Drugs used in chemotherapy, such as
Abraxane, work in different ways to stop the growth of tumor cells, either by killing the
cells or by stopping them from dividing. Giving imiquimod together with Abraxane may kill
more tumor cells.