Topical Imiquimod 5% Cream for Treatment of Cutaneous Neurofibromas in Adults With Neurofibromatosis 1
Status:
Completed
Trial end date:
2013-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine if imiquimod cream can reverse the growth of
neurofibromas. Imiquimod is a skin cream that works by stimulating the body's immune system
to respond to tumors. Imiquimod cream is approved for use in patients with various skin
lesions, including actinic keratosis, superficial basal cell carcinoma, and external genital
warts. Information from these studies, as well as previous laboratory studies, suggest that
imiquimod cream may help shrink neurofibromas or keep them from growing.