Topical Garlic Concentrate for Alopecia Areata in Children

• Status: Terminated
• Trial end date: 2017-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Management of pediatric alopecia is particularly challenging given the chronicity of the condition, limited therapeutic response and devastating psychological effects. There is a paucity of safe and effective therapies in this population.

The investigators propose to conduct and open label, prospective cohort pilot study using topical garlic concentrate ( GarlicRich) for treatment of children with alopecia areata. Study medication will be applied topically on affected area of the skin daily for 6 months. Follow up visits will occur monthly to access the efficacy and safety of the proposed treatment .

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Elena Pope
• Collaborator: Dermatology Foundation

Criteria

Inclusion Criteria:

• Children aged 4 years and older up to 18 years of age

• Patches of alopecia areata that affect less than 50% of the scalp.

• Alopecia of at least 1 year duration without evidence of regrowth

• Informed written consent

Exclusion Criteria:

• Any children experiencing significant spontaneous regrowth of terminal hair at the baseline visit.

• Any children treated with a topical, (including shampoos with active ingredients like minoxidil or clobetasol), intralesional or systemic agent likely to cause regrowth in alopecia areata within the past month from the baseline visit and during study period.

• Children with history of hypersensitivity to garlic.

• Children with widespread alopecia areata as alopecia totalis, universalis, ophiasis or diffuse Alopecia Areata.