Topical Cyclosporine for the Treatment of Dry Eye in Patients Infected With the Human Immunodeficiency Virus
Status:
Unknown status
Trial end date:
2008-11-01
Target enrollment:
Participant gender:
Summary
This study evaluates the use of topical cyclosporine 0.05% and sodium carboxymethylcellulose
0.5% for the treatment of dry eye disease in patients infected with the human
immunodeficiency virus.
Twenty HIV-positive-patients were selected from the Department of Infectious Diseases of the
Federal University of Rio de Janeiro Hospital. Dry eye diagnosis was based on a dry eye
questionnaire (Ocular Surface Disease Index - OSDI®), Schirmer I Test, break up time and 1%
rose bengal staining of the ocular surface. The patients were divided into two groups with
ten patients. Group I received sodium carboxymethylcellulose 0.5% drops and group II received
sodium carboxymethylcellulose 0,5% drops and topical cyclosporine 0.05% for six months.