The purpose of this study is to see if curcumin can reverse a cervical precancerous state by
looking at people who have the condition and intervening with a study drug or placebo (an
inactive drug), prior to planned therapeutic loop electrosurgical excision procedure (LEEP)
which is a treatment procedure for removing cervical cancer. 40 women with high grade
squamous intraepithelial lesion (HSIL) of the cervix will be enrolled to either insert 2000
mg capsule of curcumin or a placebo in their vagina once a week for 12 weeks. After a 4 week
long washout period the participants will then undergo removal of the precancerous cells as
recommended standard of care. Participants will have regular monthly visits for the duration
of the study.