Topical Application of GTN 0.4% in the Treatment of Anismus Following Stapled Haemorrhoidopexy

• Status: Completed
• Trial end date: 2010-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study wants demonstrate that the use of 0.4% nitroglycerin ointment can reduce the postoperative pain related to anorectal spasm (anismus) while performing a stapled haemorrhoidopexy.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Roma La Sapienza
• Treatments: Ketorolac Tromethamine; Lidocaine; Nitroglycerin

Criteria

Inclusion Criteria:

• Patients with symptomatic II-III grade haemorrhoids and rectal mucosal prolapse

• Adults aged ≤ 75, male or female

Exclusion Criteria:

• Concomitant ano-rectal disease (fissure, fistula, abscess, inflammatory bowel disease, rectal cancer)