Topical Amitriptyline and Ketamine Cream in Treating Peripheral Neuropathy Caused by Chemotherapy in Cancer Patients
Status:
Completed
Trial end date:
2013-11-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Topical cream containing amitriptyline and ketamine may help relieve pain,
numbness, tingling, and other symptoms of peripheral neuropathy. It is not yet known whether
topical amitriptyline and ketamine cream is more effective than a placebo in treating
peripheral neuropathy caused by chemotherapy.
PURPOSE: This randomized phase III trial is studying the side effects and how well topical
amitriptyline and ketamine cream work compared with a placebo in treating peripheral
neuropathy caused by chemotherapy in patients with cancer.
Phase:
Phase 3
Details
Lead Sponsor:
Gary Morrow
Collaborator:
National Cancer Institute (NCI)
Treatments:
Amitriptyline Amitriptyline, perphenazine drug combination Ketamine