Topical 1% Methotrexate Gel Versus Clobetasol Propionate in Patients With Psoriasis
Status:
COMPLETED
Trial end date:
2023-12-31
Target enrollment:
Participant gender:
Summary
A pilot study on the formulation of topical methotrexate was conducted. Patients after baseline evaluation were randomly placed into either topical 1% methotrexate gel or clobetasol propionate 0.05% ointment which was applied for 6 weeks. PASI score was assessed at two-week intervals for a total of eight weeks. Blood chemistry parameters, whole abdomen ultrasound, and adverse drug reactions while on treatment and after eight weeks were monitored as secondary outcome measures.
Phase:
EARLY_PHASE1
Details
Lead Sponsor:
Dr. Jose N. Rodriguez Memorial Hospital and Sanitarium