Tolerability and Efficacy of High Dose Escitalopram for the Treatment of Obsessive-Compulsive Disorder (OCD)
Status:
Completed
Trial end date:
2006-12-01
Target enrollment:
Participant gender:
Summary
Objectives: To evaluate tolerability and efficacy of escitalopram treatment in high dose than
20-50 mg/d in out-patients with OCD Type of the study: Open label, prospective study.
Number of patients: 100 patients with OCD
Duration of the study: 18-weeks of active treatment, 8-visits:
Dose titration:
One week of 10mg Four weeks of 20mg After 4 weeks of 20mg treatment- if partial/no response,
according to YBOCS score and clinical judgment, dose increase of up to 50mg depending on
response, adverse events, patient preference and judgment of the clinician 12 weeks follow up
on high dose. Total of 18 weeks of follow-up.