Overview

Tocotrienol and Bevacizumab in Metastatic Colorectal Cancer

Status:
Recruiting
Trial end date:
2023-10-01
Target enrollment:
Participant gender:
Summary
This double blind, randomized phase II trial will investigate whether the addition of tocotrienol will improve the effect and lower the toxicity of standard chemotherapy and bevacizumab. Half of the patients will receive tocotrienol and the other half placebo. Treatment is planned for a period of maximum six months and will be discontinued earlier in case of progression or unacceptable toxicity.
Phase:
Phase 2
Details
Lead Sponsor:
Vejle Hospital
Treatments:
Bevacizumab
Calcium
Calcium, Dietary
Capecitabine
Fluorouracil
Leucovorin
Levoleucovorin
Oxaliplatin
Tocopherols
Tocotrienols
Vitamin E